News for Healthier Living
EGFR Inhibitor-Linked Cytokine Storms: Study Uncovers the Trigger
 In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events (irAEs) that occur when the epidermal growth factor receptor (EGFR) inhibitor osimertinib is combined with immune checkpoint inhibitors (ICIs). Using a preclinical mouse model, the team found that this drug duo activates the IL-6/JAK/STAT3 signaling pathway in liver macrophages, unleashing a cytokine storm-like inflammatory response. Importantly, the addition of the JAK inhibitor ruxolitinib successfully dampened this response, significantly lowering levels of key inflammatory markers in the bloodstream. These findings point to a viable path forward in reducing the life-threatening toxicity associated with combination cancer therapies.
June 5, 2025
June 6 2025June 5 2025June 4 2025June 3 2025June 2 2025June 1 2025May 31 2025May 30 2025May 29 2025May 28 2025 - World No Tobacco Day 2025: Unmasking Big Tobacco's Youth Marketing Playbook
- Scientists Find Promise in a New Peptide Drug to Combat a Deadly Brain Cancer
- The Medical Minute: The ABCs of Diabetes
- Helping Kids Have a Safe Summer: 12 Tips from Johns Hopkins Pediatricians
- How to Help Teen Drivers Stay Safe on the Road
- Mayo Clinic Experts Present Key Cancer Research Findings at ASCO
- Wildfire Pollution May Lower Survival Chances for Lung Cancer Patients
- Rural Georgians Lack Access to Alzheimer's Disease Treatment
- AI-Driven Model Supports Safer and More Precise Blood Sugar Management After Heart Surgery
- Understanding Brain Tumors: What You Need to Know
- Having Your Child's Tonsils and Adenoids Out May Help with Snoring, Mouth Breathing
- Will This Year's Flu Shot Protect You? The Answer Is Hidden in Your Blood
- John Theurer Cancer Center Presents Innovative Cancer Research at Major Annual Cancer Meeting, Offering New Hope for Patients
- Understanding How a Rare Brain Wasting Disease Hides in Neurons For Decades
- T Cells Take Up Residence in the Healthy Brain Via a Gut-Fat-Brain Axis
- Immune Checkpoint Inhibitors 'High-Risk Yet Promising' for Cancer Patients Who Undergo Organ Transplant
- Singing to Babies Improves Their Moods
- Kahlert Institute for Addiction Medicine Finds Innovative Approaches to Fighting Fourth Wave of Opioid Public Health Crisis
- Research Project Studies High Doses of an Opioid Abuse Disorder Medication Among Veterans
- Why the FDA Recalled Six Popular Acne Products
- Yale Scientists Uncover Sex Differences in Recalling and Reporting of Family History of Alzheimer's Disease
- Medical Cannabis Reduces Pain, Preserves Cognition, Study Reveals
- After Mild Stroke, More Sleep or Time Spent Trying to Sleep Tied to Thinking Problems
- Shedding Pounds in Middle Age Could Add Years to Your Life, Study Finds
- RFK Jr. Ends COVID Vaccine Urging for Healthy Kids, Pregnant Women
- Miley Cyrus Reveals Rare Condition That Shapes Her Signature Voice
- Paracetamol to Poisoning: When Medicines Harm Instead of Heal
- Mother's Warmth in Childhood Influences Teen Health by Shaping Perceptions of Social Safety
- Standardized Huddle Process Improves Response to Unprofessional Behaviors in Health Care Settings
- One in Three Youth with Mental Health Crisis Spent Over 12 Hours in Emergency Department Waiting for Psychiatric Bed
- Vascular Sleuth Unlocks Origins of Congenital Limb Deficiencies--Beyond Thalidomide
- EQUAL Study Launches Lung Cancer Screening Trial for People at High Risk
- Helmets Save Lives, Head-To-Head Motorcycle Study Finds
- New Electrode Design Might Help Spasms, Pain, Paralysis
- AI Helps ID Candidates For Targeted Breast Cancer Treatment
- Preschool BMI Can Predict Childhood Obesity Risk
- Climate Change Could Be Fueling Female Cancer Deaths
- Weight-Loss Drugs May Lower Risk Of Obesity-Related Cancers
- Cardiorespiratory Effects of Wildfire Smoke Particles Can Persist for Months, Even After a Fire Has Ended
May 27 2025May 26 2025May 25 2025May 24 2025May 23 2025
|
|
|
|
|