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High-Fat Diet Accelerates Breast Cancer Tumor Growth and Invasion

A multidisciplinary team wanted to find the best diet to slow tumor growth after a breast cancer diagnosis. Instead, they found one that accelerated it: a high-fat diet. The researchers engineered a tumor model using a human plasmalike medium to re-create a more realistic microenvironment around tumors, and this allowed them to replicate the biochemical effects of nutrients from food. They discovered a high-fat diet accelerates tumor growth and invasion and causes an increase in the enzyme MMP1, which is associated with a poor prognosis.

March 3, 2026


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